Rainer Schreiber Selected Research

Chlorides

3/2022	Expression of SLC26A9 in Airways and Its Potential Role in Asthma.
1/2022	Systems Approaches to Unravel Molecular Function: High-content siRNA Screen Identifies TMEM16A Traffic Regulators as Potential Drug Targets for Cystic Fibrosis.
10/2021	The chloride channel CFTR is not required for cyst growth in an ADPKD mouse model.
4/2021	Loss of PKD1 and PKD2 share common effects on intracellular Ca2+ signaling.
1/2021	TMEM16A deficiency: a potentially fatal neonatal disease resulting from impaired chloride currents.
1/2020	Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo.
1/2020	TMEM16A drives renal cyst growth by augmenting Ca2+ signaling in M1 cells.
1/2019	Lipid Peroxidation Drives Renal Cyst Growth In Vitro through Activation of TMEM16A.
11/2017	Bicarbonate in cystic fibrosis.
1/2017	Epithelial Chloride Transport by CFTR Requires TMEM16A.

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Rainer Schreiber Research Topics

Disease

23	Cystic Fibrosis (Mucoviscidosis) 01/2022 - 04/2003
10	Neoplasms (Cancer) 01/2022 - 02/2007
9	Cysts 10/2021 - 03/2014
5	Lung Diseases (Lung Disease) 11/2017 - 04/2003
4	Asthma (Bronchial Asthma) 03/2022 - 01/2019
4	Autosomal Dominant Polycystic Kidney (ADPKD) 10/2021 - 05/2014
4	Hemorrhage 03/2016 - 03/2014
4	Carcinoma (Carcinomatosis) 07/2009 - 01/2007
3	Infections 10/2021 - 03/2016
3	Inflammation (Inflammations) 07/2021 - 11/2008
3	Squamous Cell Carcinoma of Head and Neck 01/2020 - 01/2012
3	Scott Syndrome 02/2016 - 03/2014
3	Diarrhea 06/2015 - 09/2007
3	Colonic Neoplasms (Colon Cancer) 08/2008 - 02/2007
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 01/2019
2	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2019 - 01/2016
2	Hypoxia (Hypoxemia) 12/2016 - 03/2014
2	Constipation 01/2014 - 10/2004
2	Vitelliform Macular Dystrophy 02/2010 - 02/2008
2	Macular Degeneration (Age-Related Maculopathy) 02/2008 - 09/2007
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2022
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2022
1	Human Influenza (Influenza) 01/2022
1	Pneumonia (Pneumonitis) 10/2021
1	Metaplasia 05/2021
1	Diseases Newborn Infant 01/2021
1	Alkalosis 01/2020
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2020
1	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 03/2019
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2019
1	Hearing Loss (Hearing Impairment) 03/2016
1	Dystonia (Limb Dystonia) 03/2016
1	Levin type Osteogenesis imperfecta 03/2016
1	Ataxia (Dyssynergia) 03/2016
1	Rotavirus Infections 06/2015
1	Infertility (Sterility) 05/2015
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2014
1	Colorectal Neoplasms (Colorectal Cancer) 01/2014
1	Dehydration (Water Stress) 08/2012

Drug/Important Bio-Agent (IBA)

15	ChloridesIBA 03/2022 - 01/2007
14	Chloride Channels (Chloride Channel)IBA 01/2022 - 04/2003
12	Proteins (Proteins, Gene)FDA Link 03/2019 - 06/2002
9	AnoctaminsIBA 01/2022 - 08/2011
9	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 04/2021 - 02/2005
7	CalciumIBA 03/2019 - 11/2011
6	Anoctamin-1IBA 04/2021 - 05/2014
5	Pharmaceutical PreparationsIBA 01/2022 - 02/2018
5	ElectrolytesIBA 08/2012 - 02/2002
5	BestrophinsIBA 02/2010 - 09/2007
4	Niclosamide FDA Link 01/2022 - 01/2019
4	Phospholipids (Phosphatides)FDA LinkGeneric 03/2019 - 03/2014
4	Adenosine Triphosphate (ATP)IBA 01/2017 - 01/2010
4	CollagenIBA 02/2016 - 03/2014
3	Bicarbonates (Hydrogen Carbonate)IBA 01/2022 - 01/2017
3	Ion Channels (Ion Channel)IBA 02/2016 - 08/2008
2	Small Interfering RNA (siRNA)IBA 01/2022 - 09/2013
2	CytokinesIBA 01/2021 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 05/2011
2	Adenosine Monophosphate (AMP)IBA 05/2014 - 11/2008
2	Peptides (Polypeptides)IBA 01/2014 - 05/2011
2	SaltsIBA 09/2013 - 02/2007
2	Ether (Diethyl Ether)IBA 08/2008 - 02/2007
2	Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA 02/2007 - 01/2007
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022
1	AntioxidantsIBA 10/2021
1	Transcription Factors (Transcription Factor)IBA 07/2021
1	polycystic kidney disease 2 proteinIBA 06/2021
1	polycystic kidney disease 1 proteinIBA 06/2021
1	Interleukin-8 (Interleukin 8)IBA 01/2021
1	Interleukin-13IBA 01/2021
1	MucinsIBA 01/2021
1	Secretin FDA Link 01/2020
1	BenzbromaroneIBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	Phospholipases A2 (Phospholipase A2)IBA 03/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019
1	AnionsIBA 02/2018
1	LipidsIBA 01/2018
1	InflammasomesIBA 01/2018
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2017
1	PhosphatidylserinesIBA 02/2016
1	CalpainIBA 02/2016
1	Retinaldehyde (Retinal)IBA 05/2015
1	Tannic Acid FDA Link 05/2014
1	MorpholinosIBA 05/2014
1	Histone Deacetylases (Histone Deacetylase)IBA 03/2014
1	Prolyl-Hydroxylase InhibitorsIBA 03/2014
1	Acetates (Acetic Acid Esters)FDA Link 03/2014
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 03/2014
1	ColforsinIBA 03/2014
1	chetominIBA 03/2014
1	Epithelial Sodium ChannelsIBA 09/2013
1	INO-4995IBA 01/2013
1	IonsIBA 08/2012
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 07/2012
1	Cyclin D1IBA 07/2012
1	Casein Kinases (Casein Kinase)IBA 11/2011
1	Phosphotransferases (Kinase)IBA 11/2011

Therapy/Procedure

5	Therapeutics 04/2021 - 10/2009
1	Glycemic Control 01/2016